发明名称 |
Antisense nucleic acids for the prevention and treatment of disorders in which expression of c-erbB plays a role |
摘要 |
The present invention is related to an antisense-nucleic acid or effective derivatives thereof hybridizing with an area of the messenger RNA (mRNA) or the DNA, encoding the p185erbB-2 receptor (also termed c-erbB-2, HER2 or neu), a pharmaceutical composition, comprising an antisense nucleic acid or effective derivatives thereof hybridizing with an area of the messenger RNA (mRNA) or the DNA, encoding the c-erbB-2 receptor as well as the use of said antisense nucleic acids and derivatives thereof for the manufacturing of a pharmaceutical composition for the treatment of neoplasms and/or immune diseases and/or diseases involving pathological angiogenesis.
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申请公布号 |
US6365345(B1) |
申请公布日期 |
2002.04.02 |
申请号 |
US19960666341 |
申请日期 |
1996.08.15 |
申请人 |
BIOGNOSTIK GESELLSCAHFT FUER BIOMOKEKULARE DIAGNOSTIK MBH |
发明人 |
BRYSCH WOLFGANG;SCHLINGENSIEPEN KARL-HERMANN;SCHLINGENSIEPEN REIMAR;SCHLINGENSIEPEN GEORG-FERDINAND |
分类号 |
C12N15/09;A61K31/70;A61P9/00;A61P35/00;A61P37/00;C07H21/00;C07H21/04;C12N15/113;C12Q1/68;(IPC1-7):C07H21/04;C12N15/85 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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