发明名称 |
Rekombinanttientsyymien käyttö GDP-L-fukoosin ja fukosyloitujen glykaanien valmistamiseksi |
摘要 |
Use of recombinant enzymes for the preparation of GDP-L-fucose and fucosylated glycans is disclosed. GDP-L-fucose functions as a fucose donor in the biosynthetic route leading to the fucosylated glycans, which have therapeutic utility. A process for preparing GDP-L-fucose and fucosylated glycans, and means useful in the process are provided. Said means include enzymes, chimeric enzymes, DNA sequences, genes, vectors and host cells. An assay for the determination of GDP-fucose and fucosyl-transferase, and a test kit therefore are also provided. <IMAGE> |
申请公布号 |
FI20002114(A) |
申请公布日期 |
2002.03.27 |
申请号 |
FI20000002114 |
申请日期 |
2000.09.26 |
申请人 |
MEDICEL OY, |
发明人 |
RENKONEN,RISTO;MATTILA,PIRKKO;HIRVES,LAURA;HORTLING,SOLVEING;KALLIOINEN,TUULA;KAURANEN,SIRKKA-LIISA;JAERVINEN,NINA;MAEKI,MINNA;NIITTYMAEKI,JAANA;RAEBINAE,JARKKO |
分类号 |
C12N1/15;C12N1/19;C12N9/04;C12N9/10;C12N9/12;C12N9/88;C12N9/90;C12N15/53;C12N15/54;C12N15/60;C12P19/18;C12P19/32 |
主分类号 |
C12N1/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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