发明名称 Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
摘要 The invention relates to the use of compounds of general formula (I) wherein R<1> to R<5> are independently selected from the group consisting of hydrogen, branched and unbranched C1-C4--alkyl groups, branched and unbranched C1-C4--alkoxy groups, branched and unbranched C1-C4--alkythio groups, trifluoromethyl groups, C6-C10--aryloxy groups, C7-C11--aralkyloxy groups, C1-C5--acyloxy groups, C6-C10--aroyloxy groups, C1-C4--alkylsulfonyloxy groups, C6-C10--arylsulfonyloxy groups, linear and branched C1-C4--alkoxycarbonyl groups, amino, mono(C1-C5-Alkyl)amino and di(C1-C5--alkyl)amino groups, carbamoyl, N-mono(C1-C5--alkyl)carbamoyl and N-bi(C1-C5--alkyl)carbamoyl groups, methylene dioxy groups, hydroxy groups, hydroxymethyl groups, and fluorine and chlorine; R is selected from the group consisting of hydrogen and linear and branched alkyl groups; and (chin.) represents a 3-quinuclidinyl or a 2,3-dehydro-3-quinuclidinyl group, or the physiologically tolerable salts of said compounds, for producing a medicament against illnesses whereby stimulating the nicotinic acetylcholine receptors leads to an improvement in the clinical picture.
申请公布号 DE10045112(A1) 申请公布日期 2002.03.21
申请号 DE20001045112 申请日期 2000.09.11
申请人 MERCK PATENT GMBH 发明人 HOELZEMANN, GUENTER;SCHIEMANN, KAI;BOETTCHER, HENNING;LEIBROCK, JOACHIM
分类号 A61K31/439;A61P25/28;C07D453/02;(IPC1-7):C07D453/02 主分类号 A61K31/439
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