| 摘要 |
Novel scavenger receptors having an SR structure and a collectin-like structure which are proteins having the amino acid sequences of SEQ ID NOS:2, 4 and 24 or proteins having comparable properties thereto, which are usable in clarifying the functions of macrophages and basal immunity, in clarifying the onset mechanisms of various diseases such as arteriosclerosis, diabetic complications, re-constriction after angioplasty and bacterial infection, in diagnosing, preventing and treating these diseases and in developing reagents and drugs therefor; and molecules related thereto such as derivatives or fragments thereof, isolated polynucleotides containing base sequences encoding the same, antibodies and antagonists. A treatment method by using these receptors is also disclosed. |
