| 摘要 |
Pharmaceutical compositions exhibiting thrombopoietin receptor agonism, whic h contain as the active ingredient compounds of the general formula (I): X1-Y1 - Z1-W1 prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them wherein X1 is optionally substituted aryl, optionally substituted heteroaryl, or the like; Y1 is -NRACO-(CH2)0-2- (wherein RA is hydrogen or the like) or the like; Z1 is optionally substituted phenylene or the like; and W1 is a group of the general formula (II): (II) (wherein R1, R 2, R3 and R4 are each independently hydrogen, optionally substituted lower alky l, or the like; and the broken line represents the presence or absence of a bond), or the like. |
