发明名称 AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE
摘要 There are provided novel compounds of formula (I) wherein R<1>, R<2>, X, Y and Z are as defined in the Specification and optical isomers, racemates and tautomers thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme nitric oxide synthase.
申请公布号 WO0146171(A1) 申请公布日期 2001.06.28
申请号 WO2000SE02540 申请日期 2000.12.14
申请人 ASTRAZENECA AB;CHEN, DEBORAH;EMPFIELD, JAMES;MACDONALD, JAMES;MATTES, KENNETH;MURRAY, ROBERT;PHILLIPS, EIFION;SCHMITTHENNER, HANS 发明人 CHEN, DEBORAH;EMPFIELD, JAMES;MACDONALD, JAMES;MATTES, KENNETH;MURRAY, ROBERT;PHILLIPS, EIFION;SCHMITTHENNER, HANS
分类号 A61P9/00;A61P9/10;A61P25/06;A61P25/16;A61P25/18;A61P25/28;A61P29/00;C07D307/68;C07D333/38;C07D409/12 主分类号 A61P9/00
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