发明名称 Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
摘要 The present invention relates to a method for preventing and/or reducing cellular and tissue damage caused by reactive oxygen metabolites (ROMs) released by phagocytic or endothelial cells in response to various disease states or pathologies. The methods of the present invention are useful in preventing and treating a variety of disease states or pathological situations in which ROMs are produced and released. The methods of the present invention contemplate reducing ROM-mediated damage by reducing the production and release of ROMs.
申请公布号 US6242473(B1) 申请公布日期 2001.06.05
申请号 US19990227455 申请日期 1999.01.08
申请人 MAXIM PHARMACEUTICALS, INC. 发明人 HELLSTRAND KRISTOFFER;HERMODSSON SVANTE;GEHLSEN KURT R.
分类号 A61K45/00;A61K31/00;A61K31/015;A61K31/33;A61K31/355;A61K31/375;A61K31/4045;A61K31/417;A61K38/44;A61K45/06;A61P1/00;A61P9/10;A61P11/00;A61P25/16;A61P25/28;A61P29/00;A61P31/00;A61P31/14;A61P37/00;A61P37/02;A61P39/00;A61P39/06;(IPC1-7):A61K31/417 主分类号 A61K45/00
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