发明名称 Pharmaceutical composition for inducing cytotoxic response of T-lymphocytes
摘要 <p>A compsn. is new, and comprises an antigen (I), except an albumin, mixed with an antigen formulation (II) consisting of: a stabilising detergent; a micelle-forming agent; and a biodegradable and biocompatible oil. (II) is a stable oil-in-water emulsion. Also new is a method for inducing a cytotoxic T-lymphocyte response in a human or animal comprising administering (I) and (II), (II) lacking an immunostimulating peptide component. (I) may be antigenic portions of HIV gp120, malaria antigens, CS protein and Sprorozoite surface protein, influenza antigens, carcinoma P21, etc. (I) also may not include a B-cell lymphoma anitgen.</p>
申请公布号 CZ288048(B6) 申请公布日期 2001.04.11
申请号 CZ19940000150 申请日期 1992.07.24
申请人 IDEC PHARMACEUTICALS CORPORATION 发明人 RAYCHAUDHURI SYAMAL;RASTETTER WILLIAM H.
分类号 A61K;A61K9/00;A61K9/107;A61K39/00;A61K39/015;A61K39/12;A61K39/39;A61P37/04;A61P39/00;(IPC1-7):A61K39/00 主分类号 A61K
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