发明名称 |
Methods for treating LHRH associated disorders with LHRH antagonists |
摘要 |
Methods for treating prostate cancer are disclosed. The methods of the invention generally feature administration to a subject of an LHRH-R antagonist, in combination with a second therapy. In one embodiment, this second therapy is performance of a procedure that removes or destroys prostatic tumor tissue, such as a radical prostatectomy, cryosurgery or X-ray therapy (external or interstitial). In another embodiment, the second therapy is treatment with an LHRH-R agonist, either simultaneous with or subsequent to LHRH-R antagonist therapy. The methods of the invention can further involve administering an antiandrogen and/or an inhibitor of sex steroid biosynthesis to the subject in combination with the LHRH-R antagonist.
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申请公布号 |
US6180609(B1) |
申请公布日期 |
2001.01.30 |
申请号 |
US19990438174 |
申请日期 |
1999.11.11 |
申请人 |
PRAECIS PHARMACEUTICALS, INC. |
发明人 |
GARNICK MARC B.;MOLINEAUX CHRISTOPHER J.;GEFTER MALCOLM L. |
分类号 |
A61K38/00;A61K38/04;A61K38/09;(IPC1-7):A61K38/00;A61K38/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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