摘要 |
The invention is directed to 1,4-dithiin- and 1,4-dithiepin- 1,1,4,4-tetroxi de derivatives useful as galanin receptor antagonists for treating disorders of the central nervous system. Pharmaceutical compositions comprising the compounds of the present invention and methods of treating conditions such a s an eating disorder, obesity, bulimia nervosa, anorexia nervosa, binge eating , diabetes, dyslipidemia, hypertension, memory loss, sleep disturbances, pain, depression, anxiety, Alzheimer's disease, senile dementia, cerebral hemorrhage, or diarrhea are also described.
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申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
REITZ, ALLEN B.;ROSS, TINA MORGAN;WANG, HAOU-YAN;SCOTT, MALCOLM K.;LEE, DANIEL H. S. |