| 摘要 |
<p>An objective of this invention is to provide a method for effectively detecting mismatches or mutations in a nucleic acid using MutM protein and a method for effectively separating a nucleic acid with mismatches using MutM protein. MutM protein has been found to be able to recognize any mismatches involving cytosine in a nucleic acid. It has also been found that, using the characteristic of the MutM protein, mismatches in a double-stranded nucleic acid can be efficiently detected and a double-stranded nucleic acid with mismatches can be separated from double-stranded nucleic acid samples.</p> |
