2'-DEOXY-ISOQUANOSINES, ISOSTERIC ANALOGUES AND ISOQUANOSINEDERIVATIVES AS WELL AS THEIR USE

摘要

2'-Deoxyisoguanosine, isosteric analogues and isoguanosine derivatives of formulae I - V, processes for their production via compounds of the general formulae a or b and reaction with aroyl isocyanates or from compounds of the general formulae VI - IX by photochemical irradiation. A further production process is the conversion of deoxyguanosines or guanosines by means of persilylation, reaction with ammonia and deamination in the 2 position. The compounds are suitable as pharmaceutical agents with antiviral efficacy.