| 发明名称 |
VITAMIN D3 MIMICS |
| 摘要 |
The present invention relates to non-secosteroidal compounds which activate and modulate the vitamin D receptor (VDR). Because the compounds of the present invention display many of the beneficial properties of 1,25(OH)2D3, but with reduced calcium mobilization effects, they may be used advantageously to treat and prevent conditions that show vitamin D sensitivity. Such disease states typically show abnormal calcium regulatory, abnormal immune responsive, hyperproliferative, and/or neurodegenerative characteristics.
|
| 申请公布号 |
WO0010958(A9) |
申请公布日期 |
2000.07.13 |
| 申请号 |
WO1999US18502 |
申请日期 |
1999.08.12 |
| 申请人 |
LIGAND PHARMACEUTICALS INCORPORATED |
发明人 |
ALLEGRETTO, ELIZABETH, A.;BOEHM, MARCUS, F.;NADZAN, ALEX, M. |
| 分类号 |
A61K31/09;A61K31/222;A61K31/336;A61P3/02;A61P3/10;A61P3/14;A61P13/00;A61P17/06;A61P17/10;A61P17/14;A61P19/00;A61P19/02;A61P19/10;A61P25/28;A61P35/00;A61P35/02;A61P37/02;C07C37/20;C07C43/23;C07C45/71;C07C49/255;C07D303/22;C07D303/23;(IPC1-7):C07C49/255;A61K31/12;A61K31/085 |
主分类号 |
A61K31/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
