Streptococcus pneumoniae proteins and immunogenic fragments for vaccines

摘要

A vaccine composition is disclosed that comprises polypeptides and fragments of polypeptides containing histidine triad residues or colled-coil regions, some of which polypeptides or fragments lie between 80 and 680 residues in length. Also disclosed are processes for preventing infection caused by S. pneumoniae comprising administering of vaccine compositions.