发明名称 Fatty acid analogs and prodrugs
摘要 Novel derivatives of fatty acid analogs that have from one to three heteroatoms in the fatty acid moiety which can be oxygen, sulfur or nitrogen, are disclosed in which the carboxy-terminus has been modified to form various amides, esters, ketones, alcohols, alcohol esters and nitriles thereof, and are useful as substrates for N-myristoyltransferase (NMT) and/or its acyl coenzyme, as anti-viral and anti-fungal agents or pro-drugs of such agents.
申请公布号 US5952377(A) 申请公布日期 1999.09.14
申请号 US19980175740 申请日期 1998.10.20
申请人 G. D. SEARLE & CO. 发明人 NUGENT, SEAN T.;MUELLER, RICHARD A.
分类号 C07C45/00;C07C59/135;C07C229/18;C07C235/06;C07C235/12;C07C235/16;C07C237/22;C07C255/13;C07C255/16;C07C271/22;C07D209/20;C07D257/04;(IPC1-7):A61K31/16;C07D233/04 主分类号 C07C45/00
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