| 发明名称 |
N-substituted piperidines as PDE4 inhibitors |
| 摘要 |
New N-substituted cyclic amines of formula: wherein: X, R1, R2 and R are as defined in the description, their optical and geometric isomers and physiologically tolerable salts thereof. The compounds of the invention are powerful PDE4 inhibitors and can be used therapeutically.
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| 申请公布号 |
US5919801(A) |
申请公布日期 |
1999.07.06 |
| 申请号 |
US19970934409 |
申请日期 |
1997.09.19 |
| 申请人 |
ADIR ET COMPAGNIE |
发明人 |
DHAINAUT, ALAIN;TIZOT, ANDRE;CANET, EMMANUEL;LONCHAMPT, MICHEL |
| 分类号 |
A61K31/4427;A61K31/443;A61K31/445;A61K31/47;A61K31/495;A61K31/505;A61P11/00;A61P11/08;A61P29/00;A61P43/00;C07D211/22;C07D401/06;C07D405/06;C07D409/06;C07D413/06;C07D417/06;(IPC1-7):A61K31/445 |
主分类号 |
A61K31/4427 |
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