摘要 |
<p>The invention concerns a novel method for preparing mequitazine and its laevo-gyrate isomer, consisting in reacting the phenothiazine derivative containing lithium with 3-methane sulphonyl oxymethyl-1-aza-bicyclo(2,2,2)-octane or its laevo-gyrate isomer, in the presence of butyllithium.</p> |