发明名称 |
INHIBITORS OF HIV REVERSIVE TRANSCRIPTASE |
摘要 |
The indole derivatives inhibit HIV reversive transcriptaseand are effective for the prevention and for the treatment of HIVinfections, as well as for the treatment of the Acquired ImmuneDeficiency Syndrome (AIDS). They are used as pure compounds. astheir pharmaceutically acceptable salts, as active components ofpharmaceutical compositions, separately or in combination withother antiviral agents, as anti-infectious agents,immunomodulators, antibiotics or vaccines. The invention alsorelates to methods of treatment of AIDS and for the prevention oftreatment of viral infections caused by HIV.
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申请公布号 |
BG62089(B1) |
申请公布日期 |
1999.02.26 |
申请号 |
BG19950099879 |
申请日期 |
1995.08.23 |
申请人 |
MERCK & CO INC |
发明人 |
WILLIAMS, THERESA M.;CICCARONE, TERRENCE M.;SAARI, WALFRED S.;WAI, JOHN S.;GREENLEE, WILLIAM J.;BALANI, SURESH K.;GOLDMAN, MARK E.;HOFFMAN, JACOB M.;LUMMA, WILLIAM C.;HUFF, JOEL R.;ROONEY, CLARENCE S.;SANDERSON, PHILIP E.;THEOHARIDES, SHARON A. |
分类号 |
A61K31/40;A61K31/4025;A61K31/403;A61K31/404;A61K31/41;A61K31/42;A61K31/425;A61K31/44;A61K31/4427;A61K31/443;A61K31/535;A61P31/12;A61P37/04;C07D209/12;C07D209/30;C07D209/42;C07D401/06;C07D401/12;C07D403/12;C07D405/06;C07D405/12;C07D413/06;C07D417/12;C07D521/00;(IPC1-7):C07D209/30 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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地址 |
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