发明名称 METHOD OF TREATING POLYCYSTIC KIDNEY DISEASE
摘要 This invention provides a method of treating or inhibiting polycystic kidney disease in a mammal in need thereof which comprises administering to said mammal a compound having formula (1) wherein X is phenyl which is optionally substituted; R and R1 are each, independently, hydrogen, halogen, alkyl, alkoxy, hydroxy, or trifluoromethyl; R2 is hydrogen, alkyl, alkoxy, hydroxy, trifluoromethyl; Y is a radical selected from the group consisting of (a), (b), (c), (d), (e), (f) and (g); R3 is independently hydrogen, alkyl, carboxy, carboalkoxy, phenyl, or carboalkyl; n = 2-4; or a pharmaceutically acceptable salt thereof, with the proviso that each R3 of Y may be the same or different.
申请公布号 CA2288705(A1) 申请公布日期 1998.11.12
申请号 CA19982288705 申请日期 1998.04.28
申请人 AMERICAN CYANAMID COMPANY 发明人 FROST, PHILIP
分类号 C07D239/94;A61K31/517;A61P13/12;A61P43/00;(IPC1-7):A61K31/505 主分类号 C07D239/94
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