| 摘要 |
PCT No. PCT/FR94/00189 Sec. 371 Date Aug. 21, 1995 Sec. 102(e) Date Aug. 21, 1995 PCT Filed Feb. 21, 1994 PCT Pub. No. WO94/19325 PCT Pub. Date Sep. 1, 1994The invention relates to a pseudo-dipeptide product obtained by coupling between histamine or methyl-substituted histamine and an amino-acid having formula <IMAGE> wherein A is a radical selected in the group comprising amine radicals, amides, lactames, urethans; R1, R'1, R2, R'2. . . Rn, R'n represent each a hydrogen atom, a hydrocarbon radical or a functional group; Y and Z represent each a hydrogen or a fluorine atom, or a hydrocarbon radical which may be substituted by one or a plurality of functional groups; and n is an integer higher than or equal to 1; the covalent bond with the histamine or the methyl-substituted histamine being a peptide bond between the carboxylic radical of the amino acid and the amine radical of the histamine. The pseudo-dipeptide products of the invention may be used in therapeutical, cosmetological and agro-alimentary applications and particularly for the treatment of cataracts.
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