发明名称 |
VACCINES CONTAINING CONJUGATES OF MODIFIED MENINGOCOCCAL POLYSACCHARIDES |
摘要 |
<p>The invention relates to chemically-modified group B polysaccharides of Neisseria meningitidis. The invention also provides vaccines in which the respective modified polysaccharides are conjugated to a protein carrier, and the like. More specifically, the present invention provides novel group B meningococcal unsaturated N-acyl derivative polysaccharides, novel conjugates of the group B meningococcal unsaturated N-acyl derivative polysaccharides, pharmaceutical compositions comprising conjugate molecules of group B meningococcal unsaturated N-acyl derivative polysaccharide fragments covalently bound to proteins, and the use of these compositions as vaccines.</p> |
申请公布号 |
CZ9703914(A3) |
申请公布日期 |
1998.05.13 |
申请号 |
CZ19970003914 |
申请日期 |
1996.06.07 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
JENNINGS HAROLD J.;PON ROBERT;LUSSIER MICHELE;MICHON FRANCIS |
分类号 |
A61K39/02;A61K;A61K39/08;A61K39/095;A61K39/385;A61P31/04;C08B37/00;(IPC1-7):A61K39/095;A61K39/116;A61K39/40 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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