发明名称 |
NOVEL HUMAN RAB PROTEINS |
摘要 |
The present invention provides four human Rab and Rab-associated proteins (designated collectively as HRAB) and polynucleotides which identify and encode HRAB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HRAB and a method for producing HRAB. The invention also provides for use of HRAB and agonists, antibodies, or antagonists specifically binding HRAB, in the prevention and treatment of diseases associated with expression of HRAB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HRAB for the treatment of diseases associated with the expression of HRAB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HRAB. |
申请公布号 |
WO9818942(A2) |
申请公布日期 |
1998.05.07 |
申请号 |
WO1997US18581 |
申请日期 |
1997.10.14 |
申请人 |
INCYTE PHARMACEUTICALS, INC.;BANDMAN, OLGA;AU-YOUNG, JANICE |
发明人 |
BANDMAN, OLGA;AU-YOUNG, JANICE |
分类号 |
A61K38/00;C07K14/47;C12N15/55 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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