发明名称 |
PRODUCTION OF CARTILAGE TISSUE USING CELLS ISOLATED FROM WHARTON'S JELLY |
摘要 |
The invention relates to the isolation and use of pre-chondrocytes from the umbilical cord, specifically from Wharton's jelly, that give rise to chondrocytes which produce cartilage. The isolated pre-chondrocytes, or the chondrocytes to which they give rise, can be mitotically expanded in culture and used in the production of new cartilage tissue for therapeutic use. "Banks" of pre-chondrocytes or chondrocytes can be stored frozen, and thawed and used to produce new cartilage tissue as needed. |
申请公布号 |
WO9817791(A1) |
申请公布日期 |
1998.04.30 |
申请号 |
WO1997US18862 |
申请日期 |
1997.10.23 |
申请人 |
ADVANCED TISSUE SCIENCES, INC. |
发明人 |
PURCHIO, ANTHONY, F.;NAUGHTON, BRIAN, A.;SAN ROMAN, JULIA |
分类号 |
C12N15/09;A61K35/12;A61K35/32;A61K38/00;A61L27/38;A61P17/00;A61P19/00;C12N5/02;C12N5/077;C12N5/10;C12N15/08;C12N15/85;C12P21/02;C12Q1/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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