发明名称 PHENOXYETHYLAMINE DERIVATIVE, PROCESS OF ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF
摘要 <p>Phenoxyethylamine derivatives of general formula (I) having high affinity for the 5-HT1A receptor, methods for preparing same, pharmaceutical compositions containing said derivatives, and their use, in particular as gastric acid secretion inhibitors or as antiemetics, are disclosed. In general formula (I), Ar is phenyl substituted by one or more substituents; and R is a C1-10 hydrocarbon radical selected from straight or branched alkyl, alkenyl or alkynyl radicals, saturated or unsaturated mono- or polycyclic cycloalkyl, cycloalkylalkyl or alkylcycloalkyl radicals; a pyridyl or isoquinolyl radical, phenyl optionally substituted by one or more substituents, and salts thereof.</p>
申请公布号 CZ9703117(A3) 申请公布日期 1998.04.15
申请号 CZ19970003117 申请日期 1996.04.05
申请人 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES 发明人 BIGG DENNIS;POMMIER JACQUES;MARTIN CHRISTIANE;ROUBERT PIERRE;DEFAUX JEAN-PIERRE
分类号 C07D217/22;A61K31/165;A61K31/17;A61K31/27;A61K31/44;A61K31/47;A61K31/472;A61P1/08;A61P9/12;A61P25/24;A61P25/26;A61P43/00;C07C231/02;C07C231/12;C07C233/25;C07C233/36;C07C233/37;C07C233/43;C07C233/62;C07C233/78;C07C235/40;C07C235/42;C07C235/50;C07C235/60;C07C237/30;C07C237/42;C07C255/54;C07C259/10;C07C271/28;C07C275/18;C07C275/24;C07C275/34;C07C323/20;C07D213/81;C07D217/26;(IPC1-7):C07C233/78;C07C235/46;A61K31/275 主分类号 C07D217/22
代理机构 代理人
主权项
地址