| 发明名称 |
USE OF INTERLEUKIN-10 TO PRODUCE A POPULATION OF SUPPRESSOR CELLS |
| 摘要 |
Interleukin-10 for producing a population of cells which are capable of inhibiting or suppressing reactions to alloantigens, for example in graftversus-host disease or tissue rejection, is described. Interleukin-10 for reducing responses in mixed lymphocyte response (MLR) is also described. Exogenous or induced endogenous IL-10 may be used for the inhibition or suppression of the reactions to alloantigens.
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| 申请公布号 |
CA2253803(A1) |
申请公布日期 |
1997.11.13 |
| 申请号 |
CA19972253803 |
申请日期 |
1997.05.02 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
DE VRIES, JAN E.;RONCAROLO, MARIA-GRAZIA;GROUX, HERVE M.;DE WAAL MALEFYT, RENE;BACCHETTA, ROSA |
| 分类号 |
A61K38/00;A61K31/00;A61K35/12;A61K38/20;A61K39/00;A61K39/395;A61P37/00;A61P37/06;C12N5/0783;C12N15/09;C12N15/24;(IPC1-7):C12N5/08;C12N5/06 |
主分类号 |
A61K38/00 |
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