发明名称 DERIVATIVES OF CAMPTOTHECIN FOR USE IN TREATING CANCER
摘要 Derivatives of camptothecin are disclosed and are represented by general formula (I), wherein when R2 is H, R1 is a C2-C4 alkyl group, a C6-C15 alkyl group, a C3-C8 cycloalkyl group, a C2-C15 alkenyl group or a C2-C15 epoxy group; and when R2 is a nitro group, R1 is a C1-C15 alkyl group, a C2-C15 alkenyl group, a C3-C8 cycloalkyl group, or an epoxy group. Processes for making these derivatives and for using them in cancer treatment are also disclosed.
申请公布号 CA2244698(A1) 申请公布日期 1997.08.07
申请号 CA19972244698 申请日期 1997.01.29
申请人 THE STEHLIN FOUNDATION FOR CANCER RESEARCH 发明人 ZHISONG, CAO;GIOVANELLA, BEPPINO C.
分类号 A01N43/42;A61F13/00;A61K9/48;A61K31/4375;A61K31/44;A61K31/4745;A61K47/00;C07D471/14;C07D491/12;C07D491/22;C07D498/14;(IPC1-7):C07D491/22;A61K31/47 主分类号 A01N43/42
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