发明名称 Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
摘要 This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
申请公布号 US5646153(A) 申请公布日期 1997.07.08
申请号 US19950439027 申请日期 1995.05.11
申请人 RHONE-POULENC RORER PHARMACEUTICALS INC. 发明人 SPADA, ALFRED P.;MYERS, MICHAEL R.;MAGUIRE, MARTIN P.;PERSONS, PAUL E.
分类号 A61K31/495;A61K31/517;A61K31/5377;C07C43/205;C07C43/225;C07C43/23;C07D213/30;C07D213/64;C07D215/14;C07D215/18;C07D215/20;C07D215/22;C07D215/233;C07D215/50;C07D239/74;C07D239/88;C07D239/91;C07D239/93;C07D239/94;C07D241/42;C07D241/52;C07D265/22;C07D277/64;C07D401/04;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D471/04;(IPC1-7):A61K31/505;A61K31/44;A61K31/47;A61K31/38 主分类号 A61K31/495
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