Diagnosis of cancer using tumor-mimetic cell surface antigen from chemically modified normal cells

摘要

A tumor-mimetic cell surface antigen (TMCSA) is produced by chemical treatment of normal human cells with fluordinitrobenzene. This TMCSA cross-reacts with tumor antigens from every type of tumor examined of any histopathologic type. Cancer is detected by detecting the presence of lymphocytes sensitized to tumor antigens based on their reactivity with TMCSA in a binding assay or lymphocyte stimulation assay.