发明名称 CATIONIC POLYACRYLATES AND POLY(ALKYL) ACRYLATES OR THE CORRESPONDING ACRYLAMIDES FOR USE IN SYNTHETIC TRANSFECTION OR BLOCKING SYSTEMS
摘要 <p>The present invention relates to a synthetic transfection or blocking system comprising as a carrier a cationic, water soluble or water dispersible polyacrylate, a polyacrylamide, a poly(C1-6 alkyl)acrylate, or a poly(C1-6 alkyl)acrylamide. In addition, it relates to a method for introducing DNA fragments in target cells, comprising contacting these DNA fragments with a polyacrylate, polyacrylamide, a poly(C1-6 alkyl)acrylate or a poly(C1-6 alkyl)acrylamide, which is at least partially substituted with cationic substituents and subsequently contacting the obtained transfection system with target cells. Finally, the invention involves the use of a polyacrylate, a polyacrylamide, a poly(C1-6 alkyl)acrylate, or a poly(C1-6 alkyl)acrylamide, which is at least partially substituted with cationic substituents as a DNA carrier system.</p>
申请公布号 WO1997015680(A1) 申请公布日期 1997.05.01
申请号 NL1996000416 申请日期 1996.10.25
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