发明名称 |
USE OF A gamma -RAR-SPECIFIC AGONIST LIGAND TO INCREASE APOPTOSIS RATE |
摘要 |
The use of at least one gamma -RAR receptor-specific agonist ligand to prepare a pharmaceutical composition for increasing the rate of apoptosis in at least one cell population in which apoptosis may be induced by activating gamma -RAR receptors is disclosed. The composition is particularly useful for treating a disease or disorder related to an insufficient rate of apoptosis in at least one cell population in which apoptosis may be induced by activating gamma -RAR receptors. The use of at least one gamma -RAR receptor-specific agonist ligand as the apoptosis inducer in a cosmetic composition is also disclosed. Said composition may be used to prevent and/or control photo-ageing or chronological ageing of the skin. |
申请公布号 |
WO9713505(A2) |
申请公布日期 |
1997.04.17 |
申请号 |
WO1996FR01568 |
申请日期 |
1996.10.08 |
申请人 |
CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES;FESUS, LASZLO;SZONDY, ZSUZSA;REICHERT, UWE |
发明人 |
FESUS, LASZLO;SZONDY, ZSUZSA;REICHERT, UWE |
分类号 |
C07D333/38;A61K8/00;A61K8/36;A61K8/368;A61K8/40;A61K8/41;A61K8/46;A61K8/49;A61K31/19;A61K31/192;A61K31/195;A61K31/34;A61K31/343;A61K31/35;A61K31/352;A61K31/38;A61K31/381;A61K31/40;A61K31/60;A61K45/00;A61P1/16;A61P3/08;A61P3/10;A61P17/00;A61P17/06;A61P29/00;A61P31/12;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D207/34;C07D307/91;C07D311/58 |
主分类号 |
C07D333/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|