发明名称 |
Polyvinylalcohol coated capillary electrophoresis columns |
摘要 |
Coated capillary electrophoresis columns and methods for their use in electrophoretic separations are disclosed. The coated capillary columns include a length of tubing having an interior surface having an interconnected polymeric coating. The interconnected polymeric coating includes a hydrophobic hydrocarbon polymeric functionality covalently bound to the interior surface and polyvinylalcohol interconnected with the hydrophobic polymeric functionality. Exemplary columns are prepared by causing a Si-OH reactive compound, having a hydrophobic polymeric functionality, to react with Si-OH functionalities on the interior surface of capillary columns. Then causing vinyl acetate to polymerize in contact with the hydrophobic polymeric functionality and hydrolyzing the resulting polyvinylacetate forms a coating of interconnecting hydrophilic and hydrophobic polymers.
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申请公布号 |
US5605613(A) |
申请公布日期 |
1997.02.25 |
申请号 |
US19950379383 |
申请日期 |
1995.01.27 |
申请人 |
BECKMAN INSTRUMENTS, INC. |
发明人 |
SHIEH, CHIA-HUI |
分类号 |
G01N27/447;(IPC1-7):C25B7/00 |
主分类号 |
G01N27/447 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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