发明名称 |
NEW SUBSTITUTED AZETHIDINONES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, TREATMENT METHOD |
摘要 |
FIELD: organic chemistry. SUBSTANCE: product: substituted azethidinones of the general formula (I) where: Rmeans (a) or (b) where Rmeans carboxy-C-alkyl, benzylhydroxycarbonyl-C-alkyl or t-butoxycarbonyl-C-alkyl where Q means covalent bond or (C). Y means (d) or (e) or covalent bond. The synthesized compounds are powerful inhibitors of elastase and can be used as antiinflammatory and antidegenerative agents. EFFECT: improved method of synthesis, enhanced effectiveness. |
申请公布号 |
RU95109936(A) |
申请公布日期 |
1997.01.10 |
申请号 |
RU19950109936 |
申请日期 |
1993.10.26 |
申请人 |
MERK EHND KO.;INK. (US) |
发明人 |
DZHEJMS P.DOKHERTI;KONRAD P.DORN;FILIP L.DJURE;POL EH.FINK;MAL'KOM MAKKOSS;SANDER G.MILLS;SHRENIK K.SHAKH;SOUMIA P.SAKHOO;DZHEFFRI DZH.KHEJL;TOMAS DZH.LANZA;UIL'JAM K.KHAGMANN |
分类号 |
A61K31/395;A61K;A61K31/397;A61K31/40;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/455;A61K31/495;A61K31/505;A61K31/53;A61K31/535;A61K31/55;A61P7/00;A61P9/10;A61P11/00;A61P29/00;A61P35/02;A61P43/00;C07D;C07D205/08;C07D401/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12;C07D453/02;C07D521/00 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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