VARIANTES DE INTERLEUQUINA-3(IL-3) CON CISTEINA AÑADIDA Y SUS MODIFICACIONES QUIMICAS.,申请号ES19900907849T-传众专利搜索

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发明名称	VARIANTES DE INTERLEUQUINA-3(IL-3) CON CISTEINA AÑADIDA Y SUS MODIFICACIONES QUIMICAS.
摘要	SE PRESENTAN VARIANTES AÑADIDAS DE CISTEINA ("CAVS") DE POLIPEPTIDOS QUE TIENEN UNO O MAS RESIDUOS DE CISTEINA SUSTITUIDOS POR RESIDUOS SELECCIONADOS DE AMINOACIDOS QUE OCURREN DE MANERA NATURAL O INSERTADOS EN LA SECUENCIA POLIPEPTIDA Y QUE PREFERIBLEMENTE SE HAN SEGUIDO MODIFICANDO ELIMINANDO CIERTOS AMINOACIDOS DE TERMINAL N. DICHAS CAVS SE PUEDEN SEGUIR MODIFICANDO SI SE ACOPLAN COMPUESTOS REACTIVOS SULFHIDRILICOS AL RESIDUO (S) DE CISTEINA INTRODUCIDO SIN PERDIDA DE BIOACTIVIDAD PARA PRODUCIR IL-3, G-CSF O EPO SELECCIONADOS HOMOGENEAMENTE MODIFICADOS Y COMPOSICIONES FARMACEUTICAS MEJORADAS QUE LAS CONTIENEN.
申请公布号	ES2090132(T3)	申请公布日期	1996.10.16
申请号	ES19900907849T	申请日期	1990.04.19
申请人	GENETICS INSTITUTE, INC.	发明人	SHAW, GRAY;VELDMAN, GEERTRUIDA;WOOTERS, JOSEPH
分类号	A61K38/00;A61K47/48;A61P7/00;A61P7/06;C07K14/00;C07K14/505;C07K14/52;C07K14/53;C07K14/535;C07K14/54;C12N1/21;C12N15/09;C12N15/24;C12N15/27;C12P21/02;C12R1/19;(IPC1-7):C12N15/24	主分类号	A61K38/00
代理机构		代理人
主权项
地址

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