INTEGRAL RECONSTITUTION DEVICE

摘要

The device of the present invention includes a flexible container (12) having an administration port (24) and a flexible tube (30) extending therefrom. The administration port (24) includes an access membrane through which a spiked cannula can be inserted to gain access to the interior of the flexible container(12). The flexible tube (30) contains a frangible or breakaway valve (74) therein. Permanently secured to the end of the flexible tube (30) is a sheath (32) having a substantially circular base (34) and an open-ended skirt (36) including an innersurface (62) depending from the base (34). The skirt (36) includes a plurality of inwardly projecting bumps (60) intermittently spaced around the inner surface (62) to sealingly engage a standard drug vial. A sharp cannula (64) is mounted within the skin (36) to pierce the stopper of the standard drug vial to establish fluid communication between the cannula (64) and the interior of the drug vial. A peelable closure (40) is provided covering the skirt (36) opening prior to use to maintain a sterile condition of the device. A lumen (72) is provided in housing to establish fluid communication between the cannula (64) and the frangible or breakaway valve (74).