发明名称 |
DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
摘要 |
This invention provides an isolated nucleic acid molecule encoding a human Y2 receptor, an isolated protein which is a human Y2 receptor, vectors comprising an isolated nucleic acid molecule encoding a human Y2 receptors, mammalian cells comprising such vectors, antibodies directed to the human Y2 receptor, nucleic acid probes useful for detecting nucleic acid encoding human Y2 receptors, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human Y2 receptor, pharmaceutical compounds related to human Y2 receptors, and nonhuman transgenic animals which express DNA a normal or a mutant human Y2 receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human Y2 receptor.
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申请公布号 |
US5545549(A) |
申请公布日期 |
1996.08.13 |
申请号 |
US19940192288 |
申请日期 |
1994.02.03 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORPORATION |
发明人 |
GERALD, CHRISTOPHE;WALKER, MARY W.;BRANCHEK, THERESA;WEINSHANK, RICHARD L. |
分类号 |
A01K67/027;A61K31/70;A61K38/00;A61K45/00;A61K48/00;A61P1/00;A61P25/00;A61P25/08;C07H21/04;C07K14/705;C07K16/28;C12N5/00;C12N5/10;C12N15/09;C12P21/08;C12Q1/68;C12R1/91;G01N33/566;(IPC1-7):C07H21/04;C12N15/12;C12N15/63 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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