| 摘要 |
<p>The present invention provides polyunsaturated fatty acid compounds having antimalarial and/or neutrophil stimulatory activity, or anti-inflammatory activity. The polyunsaturated fatty acids contain a 16-26 carbon chain, 3-6 double bands and are covalently coupled at the carboxylic acid group to an amino acid. It is preferred that the fatty acid contains 18-22 carbons and that the amino acid is glycine or aspartic acid. Preferred compounds are η-linolenic acid-glycine, α-linolenic acid-glycine, arachidonic acid-glycine, docosahexaenoic acid-glycine, eicosapentaenoic glycine, η-linolenic acid - aspartic acid, α-linolenic acid - aspartic acid, arachidonic acid - aspartic acid, eicosapentaenoic acid - aspartic acid and docosahexaenoic acid - aspartic acid.</p> |
