发明名称 |
USE OF URINASTATIN-LIKE COMPOUNDS TO PREVENT PREMATURE DELIVERY |
摘要 |
The present invention provides a method of diagnosing and treating a pregnant female at risk for impending preterm delivery. The method comprises the step of diagnosing imminent preterm delivery by testing with a method that has a sensitivity of at least 80 % and a specificity of at least 80 %, or by testing for fetal fibronectin in the female's vaginal or cervical secretions. If imminent preterm delivery is indicated by the test, the next step comprises administering to the female a combination of a tocolytic agent, at least one urinastatin-like compound, and at least one antibiotic. Also provided is a pharmaceutical composition of MGMTSRYFYNGTSMA, RAFIQLWAFDAVKGK and an antibiotic.
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申请公布号 |
WO9512406(A1) |
申请公布日期 |
1995.05.11 |
申请号 |
WO1994US12751 |
申请日期 |
1994.11.04 |
申请人 |
ADEZA BIOMEDICAL;TERAO, TOSHIHIKO;KANAYAMA, NAOHIRO;CASAL, DAVID |
发明人 |
TERAO, TOSHIHIKO;KANAYAMA, NAOHIRO;CASAL, DAVID |
分类号 |
G01N33/50;A61K31/135;A61K31/405;A61K31/43;A61K31/545;A61K31/70;A61K33/06;A61K38/00;A61K38/55;A61K38/57;A61P13/02;A61P15/00;C07K14/81;C12P21/02;G01N33/53;(IPC1-7):A61K38/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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