发明名称 Cyclic adhesion inhibitors
摘要 The invention relates to cyclic peptides of the formula I Cyclo-(Arg-B-Asp-D-E> in which B, D and E have the meaning stated in Claim 1, and to salts thereof. These compounds act as integrin inhibitors and can be used, in particular, for the prophylaxis and treatment of circulatory disorders and in tumour therapy.
申请公布号 DE4310643(A1) 申请公布日期 1994.10.06
申请号 DE19934310643 申请日期 1993.04.01
申请人 MERCK PATENT GMBH, 64293 DARMSTADT, DE 发明人 JONCZYK, ALFRED, DR.-CHEM., 64295 DARMSTADT, DE;HOELZEMANN, GUENTER, DR.-CHEM., 64342 SEEHEIM, DE;FELDING-HABERMANN, BRUNHILDE, DR., LA JOLLA, CA., US;RIPPMANN, FRIEDRICH, DR., 69120 HEIDELBERG, DE;DIEFENBACH, BEATE, 64289 DARMSTADT, DE;KESSLER, HORST, PROF. DR.-CHEM., 85748 GARCHING, DE;HAUBNER, ROLAND, 85748 GARCHING, DE;WERMUTH, JOCHEN, 85748 GARCHING, DE
分类号 A61K38/00;A61K38/08;A61K38/12;A61P9/00;A61P19/00;A61P35/00;C07K1/113;C07K1/22;C07K7/52;C07K7/64;C07K14/75;C07K14/78;C07K17/08;(IPC1-7):C07K7/52;A61K37/02 主分类号 A61K38/00
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