发明名称 |
FLUORESCENCE POLARIZATION IMMUNOASSAY FOR AMPHETAMINE/METHAMPHETAMINE |
摘要 |
<p>This disclosure related to a method and reagents for determining amphetamine and methamphetamine in a biological fluid such as urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure for determining the presence of amphetamine and methamphetamine in a single assay and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described includes pretreatment of the biological sample to eliminate cross-reactants such as beta -hydroxyphenethylamine by preincubating the sample solely with an aqueous periodate solution having a pH from about 4.0 to about 7.5 without adjustment to an alkaline pH.</p> |
申请公布号 |
EP0279213(B1) |
申请公布日期 |
1992.10.21 |
申请号 |
EP19880100958 |
申请日期 |
1988.01.22 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BRYNES, PAUL JEFFREY;MARTINUS, JANIS ALLISON;SMITH, CATHERINE M.;MOLINA, CYNTHIA MARTHA;VAUGHAN, KENWARD SHAW |
分类号 |
G01N33/53;G01N33/533;G01N33/542;G01N33/94 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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