发明名称 |
Polyamines useful as antagonists of excitatory amino acid neurotransmitters. |
摘要 |
<p>A substantially pure compound, derived from the venom of Agelenopsis aperta spider, of the formula <CHEM> wherein each R is the same and is H or OH. The polyamines of this invention and the salts thereof antagonize excitatory amino acid neurotransmitters, which neurotransmitters affect cells of various organisms, and are useful in antagonizing said neurotransmitters, per se, in the treatment of excitatory amino acid neurotransmitter mediated diseases and conditions and in the control of invertebrate pests.</p> |
申请公布号 |
EP0436332(A2) |
申请公布日期 |
1991.07.10 |
申请号 |
EP19900313663 |
申请日期 |
1990.12.14 |
申请人 |
PFIZER INC.;NATURAL PRODUCTS SCIENCES INC. |
发明人 |
SACCOMANO, NICHOLAS ALEX;VOLKMANN, ROBERT ALFRED |
分类号 |
A61K31/405;A01N43/38;A61K31/403;A61K31/404;A61P25/00;A61P25/08;A61P25/28;C07D209/18 |
主分类号 |
A61K31/405 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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