发明名称 |
SUSTAINED RELEASE ELEMENTS |
摘要 |
The invention is concerned with a sustained release element and its manufacture. The element comprises an agent (A) capable of release from the element when the latter is in an aqueous environment and a vehicle (B) therefor, the vehicle (B) comprising a hydrophilic component such as propylene glycol, liquid polyethylene glycols or glycerol, a silicone polymer and a modulating component, such as a polyhydroxylated organic substance or a hydrophilic polymer which swells in an aqueous medium, such as a cellusolve derivative. This element is useful particularly for affording controlled release of therapeutic or diagnostic agents. In addition to controlled release, swelling properties, adhesion and/or floatability enable increased residence times to be achieved in the stomach, colon or on the mucosa of patients undergoing treatment.
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申请公布号 |
CA2027865(A1) |
申请公布日期 |
1991.04.24 |
申请号 |
CA19902027865 |
申请日期 |
1990.10.17 |
申请人 |
AQUADISCH, LOUIS M. J.;ETIENNE, ALAIN;GRISONI, BERNARD F. |
发明人 |
AQUADISCH, LOUIS M. J.;ETIENNE, ALAIN;GRISONI, BERNARD F. |
分类号 |
A61K9/00;A61K9/16;A61K9/20;A61K9/22;A61K9/26;A61K47/26;A61K47/34;A61K47/38;A61K49/00;(IPC1-7):A61K47/34;A61K47/32;A61L27/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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