发明名称 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers.
摘要 Piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers of formula <CHEM> X is N or CH; Alk is C1-4alkanediyl; R<1> and R<2> are hydrogen, C1-4alkyl or halo; R<3> is hydrogen, halo, cyano, C1-4alkyloxy, aryl or -COOR<4>, with R<4> being hydrogen, C1-4alkyl, arylC1-4alkyl, C3-6cycloalkylC1-4alkyl, C3-5alkenyl, C3-5alkynyl or C1-4alkyloxyC1-4alkyl; or R<3> is a radicai of formula <CHEM> the addition salts and stereochemically isomeric forms thereof, said compounds having antirhinoviral activity. Pharmaceutical compositions containing these compounds as active ingredient, and a method of preparing said compounds and pharmaceutical compositions.
申请公布号 EP0398425(A1) 申请公布日期 1990.11.22
申请号 EP19900201184 申请日期 1990.05.10
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 STOKBROEKX, RAYMOND ANTOINE;GRAUWELS, GILBERT ARTHUR JULES;WILLEMS, MARC
分类号 C07D275/02;A61K31/495;A61K31/496;A61P31/12;C07D261/20;C07D263/48;C07D263/58;C07D271/06;C07D271/07;C07D271/10;C07D271/113;C07D275/04;C07D275/06;C07D277/20;C07D277/42;C07D277/56;C07D277/62;C07D277/82;C07D285/08;C07D285/12;C07D285/135;C07D413/04;C07D413/12;C07D417/04;C07D417/14 主分类号 C07D275/02
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