发明名称 |
NOVEL 1ALPHA-HYDROXYVITAMIN D2 EPIMER AND DERIVATIVES |
摘要 |
The invention provides a new vitamin D2 compound, 1 alpha -hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone calcium mobilization or the differentiation of undifferentiated cells in culture, thereby evincing utility in the treatment of diseases characterized by loss of bone mass. |
申请公布号 |
AU5192590(A) |
申请公布日期 |
1990.10.09 |
申请号 |
AU19900051925 |
申请日期 |
1990.02.16 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
HECTOR F. DELUCA;HEINRICH K. SCHNOES;KATO L. PERLMAN |
分类号 |
A61K31/59;A61K31/592;A61P3/02;A61P3/14;A61P19/10;A61P43/00;C07C401/00 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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