| 发明名称 |
PHARMACEUTICAL FORMULATIONS |
| 摘要 |
The present invention relates to a new two-component pharmaceutical formulation of melphalan in which the two components comprise a) freeze-dried mephalan hydrochloride and b) a solvent-diluent comprising a citrate, propylene glycol and ethanol. Substantially pure melphalan, substantially pure melphalan hydrochloride and methods for preparing them are also described. |
| 申请公布号 |
ZA8808674(B) |
申请公布日期 |
1990.07.25 |
| 申请号 |
ZA19880008674 |
申请日期 |
1988.11.18 |
| 申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
STEPHEN WILLIAM POOLE;TIMOTHY PAUL STANLEY;GEOFFREY DIVALL;TERENCE WILLIAM PACKHAM;JOSEPH KNIGHT |
| 分类号 |
A61K9/08;A61K9/00;A61K9/14;A61K31/185;A61K31/195;A61K47/00;A61K47/08;A61K47/10;A61K47/12;A61K47/32;A61P35/00;C07B63/00;C07C229/00;C07C229/34;C07C229/36;C07C229/42 |
主分类号 |
A61K9/08 |
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