发明名称 COMPOUNDS WITH CENTRAL ANALGESIC ACTIVITY,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Derivatives of 2-aminothenol of the formula (I) and their acid-addition salts are new.In (I) R is phenyl opt. substd. by one to three substituents selected from 1-4C alkyl, 1-4C alkoxy, OH, halogen, and CF3 or R is 5- or 6-membered heteroaryl contg. one to three heteroatoms selected from 0, N and S, and opt. substd. by one of three substituents selected from R1 ad R2 are each independently 1-6C alkyl or 3-6C cycloalkyl or NR1R2 is a 5- or 6-membered heterocyclic radical which may further contain one or two heteroatoms selected from O,N, S and which is opt- substd. by one or two 1-4C alkyl gps. R3 is H or phenyl, opt. substd. by one to three substituents selected from 1-4C alkyl, 1-4C alkoxy, OH, halogen, and CF3. n is 1 or 2.
申请公布号 ZA8903704(B) 申请公布日期 1990.01.31
申请号 ZA19890003704 申请日期 1989.05.17
申请人 ZAMBON GROUP SPA. 发明人 ANGELO CARENZI;DARIO CHIARINO;DAVIDE DELLA BELLA;GIAN CARLO GRANCINI;CARLO VENEZIANI
分类号 A61K;C07D 主分类号 A61K
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