| 摘要 |
PURPOSE:To obtain a preventive for dental caries having high safety by compounding crude catechin extracted from tea leaves, fraction separated from crude catechin, fraction for crude catechin ester or pure catechin. CONSTITUTION:The objective agent is produced by compounding crude catechin extracted from tea leaves (e.g., green tea, oolong tea or black tea), fraction separated from crude catechin, fraction of crude catechin ester extract or pure catechin produced by purging those crude catechin, etc., as an active component, properly mixing the active component with conventional components such as abrasive, binder, wetting agent, forming agent, essential oil, flavor, sweetener, preservative and water and forming in the form of a drug by conventional method, It is used in the form applicable to oral cavity, e.g., dentifrice and mouthwash (e.g., toothpaste). It is effective in exterminating or suppressing the proliferation of Streptococcus mutans and remarkably preventing the generation of caries. |
