发明名称 Process for the preparation of ergolinylthioureas
摘要 Ergolinylthioureas derivatives of the general Formula I <IMAGE> (I) wherein R1 is hydrogen, lower alkyl or acyl, R2 is hydrogen, halogen or a lower alkylthio group R3 is lower alkyl, R4, R5 and R6, is hydrogen or lower alkyl, and each is identical or different, n=0, 1 or 2 and C9-C10 is a single or a double bond; are produced by reacting in an ergolin-8-ylurea compound otherwise corresponding to Formula I with a -CO-NR5R6 group in place of the -CS-Nr5R6 group is reacted with a chlorinating agent and a thiolating agent.
申请公布号 US4801714(A) 申请公布日期 1989.01.31
申请号 US19860893911 申请日期 1986.08.06
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 BIERE, HELMUT;HAFFER, GREGOR
分类号 C07D457/02;C07D457/12;(IPC1-7):C07D31/48 主分类号 C07D457/02
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