| 摘要 |
<p>The present invention relates to a new method of protection of the carboxy group in the chemistry of the compounds of beta -lactam type. According to such a method, the carboxy group is protected by being transformed into its corresponding phenyl-acetoxy-methyl ester, which is then removed by an enzymatic route by means of penicillinacylase. In particular, if the beta -lactam compound also bears a phenyl-acetamidic substituent, this latter is simultaneously hydrolysed during the same step of removal of the carboxy function protecting group.</p> |
