摘要 |
<p>A process for preparing an N-substituted nitromethylene heterocyclic compound of the following general formula:- <CHEM> wherein n is 2, 3 or 4 and R is an optionally-substituted acyl group derived from an organic acid, characterised in that an N-substituted-S-substituted aminothiol of the following general formula: R - NH - (CH2)n - S - @@@ CH - NO2 (II) wherein R and n have the meanings hereinbefore specified and Hal is a halogen atom, is reacted with a base, preferably an alkali metal or alkaline earth metal hydride or alkoxide or an alkali metal amide, in the presence of an inert solvent.</p> |