TETRAHYDROQUINOLINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, THEIR USE, AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM

摘要

Tetrahydroquinolines of the formula I (I) and acid addition salts thereof, wherein R1 denotes alkyl, phenyl, substituted phenyl or heteryl and R2 and R3 independently of one another denote hydrogen or alkyl, or R2 and R3, together with the nitrogen atom to which they are bonded, form a 5-membered or 6-membered heterocyclic ring, optionally containing a further hetero-atom grouping, such as -O-, -S- or -NH are prepared by reacting a compound of formula II (II) wherein Z denotes or and Hal denotes halogen, an amine of the formula III R2-NH-R3 (III) and optionally reacting the compound obtained with an acid to give an acid addition salt.